AAHI NEWS

Innovations • Global Impact • In The News • Our People

A Reflection of 2022 - Structure, Focus, and Growth

The successful transition from IDRI to AAHI renewed our focus on pragmatic and creative solutions to fundamental global health challenges and continued development of immune-enhancing technologies that can reach all areas of the world.

INNOVATIONS

The latest scientific breakthroughs at AAHI.

Make your products accessible to those who need them most. Collaborate with AAHI.

GLOBAL IMPACT

DECEMBER 2022

Collaboration across communities. Explore AAHI's different areas of impact.

Seattle, WA

AAHI to share progress on priority Sustainable Development Goals at GlobalWA's Goalmakers Annual Conference

Join us to discuss how we can build solutions to ensure every person has access to life-saving technology, regardless of geography or socio-economic circumstance.

Ivyland, Pennsylvania

Successful lyophilization of a thermostable subunit tuberculosis vaccine candidate containing an emulsion-based adjuvant

AAHI's tuberculosis vaccine candidate, combining our "ID93" fusion protein and GLA-SE adjuvant formulation, was successfully lyophilized by Lyophilization Technology Inc., published in Frontiers in Drug Delivery. The vaccine candidate is designed for long-term stability. 

Cape Town, South Africa

First-in-human Phase 1 / 2 clinical trial evaluating saRNA-NLC SARS-CoV-2 vaccine candidate

AAHI's SARS-CoV-2 RNA vaccine candidate, AAHI-SC2, developed in collaboration with AccessBio (a joint venture between ImmunityBio and Amyris), is currently being evaluated in a Phase 1 / 2 clinical trial sponsored by ImmunityBio in South Africa (NCT05370040). The ongoing trial has demonstrated safety of the vaccine candidate. 

Help us make impossible vaccines possible.

IN THE NEWS

By Bob Holmes

Knowable Magazine

"We've spent a lot of time working on adjuvant formulations that can shape the immune response to make it more potent, but also broader and more durable," AAHI's Senior Vice President, Formulations, Christopher Fox, PhD tells Knowable Magazine. Adjuvants are ingredients vaccine developers add to vaccines to tweak the immune system's response and may be the solution to better vaccines.

OUR PEOPLE

Collaboration across communities. Explore our different areas of impact.

AAHI was honored to receive the nonprofit "Turnaround of the Year" award from the Turnaround Management Association, which recognized AAHI's reorganization and exit from receivership.

Featured Post

November 1-4 | Boston, Massachusetts

Congratulations to Shelly Crocker LLC, Jennifer Faubion at Cairncross & Hempelmann, Avi Lipman at McNaul Ebel Nawrot & Helgren PLLC, Brett Amron at Bast Amron LLP, Neil O'Connor at Neil O'Connor LLC, Candice Decaire, Chief Strategy Officer and General Counsel, and Dr. Corey Casper, President and Chief Executive Officer.

Openings and Opportunities

Research

The Associate / Staff Scientist will be responsible for managing and executing formulation development
and stability studies, including collecting, analyzing, reviewing, and reporting bulk antigen and drug
product characterization for multiple projects.

Research

The Senior Scientist joining our RNA vaccine team will be responsible for broadening the applications of
AAHI's RNA vaccine platform to a wide range of infectious disease and oncology targets.

Learn more about our formulation technology

We partner with biotech leaders to develop vaccines and more.

Synthetic TLR4 ligand in squalene nanoemulsion

Synthetic TLR4 ligand in QS- 21 containing liposome

Synthetic TLR4 ligand in aqueous formulation

Dual agonist containing both TLR4 and TLR7/8 ligands

2nd-Gen synthetic TLR4 ligand
in squalene nanoemulsion

2nd-Gen synthetic TLR4 ligand
in QS-21 containing liposome

2nd-Gen synthetic TLR4 ligand
in aqueous formulation

Alum nanoparticle formulation, customized particle size

Synthetic TLR7/8 ligand in
squalene nanoemulsion

Synthetic TLR7/8 ligand
adsorbed to aluminum

Synthetic TLR7/8 ligand in
aqueous formulation

Nanostructured lipid carrier

See how our formulations are being used.

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